Phenotypic Diversity and Clinico-Hematological Profile of Hb E-Beta Thalassemic Children
نویسندگان
چکیده
منابع مشابه
Clinico-hematological profile of megaloblastic anemia.
Subject and Methods Twenty nine children (age range 3 months to 12 years) diagnosed as megaloblastic anemia over a period of three year (March 1993 to March 1996) were prospectively studied. All anemic children admitted with or without bleeding manifestations had their peripheral blood smear examined. Complete hemogram including platelet count and mean corpuscular volume (MCV) were also carried...
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We report a case of beta-thalassemia/Hb Tak compound heterozygote. The 7 year-old Thai boy presented with plethora since birth. Hemoglobin electrophoresis showed a major band between Hb A2 and Hb F and absent Hb A. DNA sequencing study demonstrated an AC insertion at the terminal codon of the beta-globin gene. The clinical feature of polycythemia reflected a high oxygen affinity of Hb Tak.
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ژورنال
عنوان ژورنال: Indian Journal of Hematology and Blood Transfusion
سال: 2019
ISSN: 0971-4502,0974-0449
DOI: 10.1007/s12288-019-01150-5